Welcome

We are part of the newly formed Department of Pediatric Newborn Medicine and the Division of Genetics (Department of Medicine) at Brigham and Women’s Hospital, Harvard Medical School.

Our research goal is to advance the fundamental biologic understanding of pluripotent stem cells in order to unlock their therapeutic and research potential.

We aim to apply novel cell imaging techniques, genomics approaches and computational biology to generate novel models of human disease and development using induced pluripotent stem cells.

People

  • Testimonial

    Paul Lerou, MD

    PI

    About Paul Lerou, MD

    Paul graduated from Jefferson Medical College and did his residency and chief residency at Boston Children’s Hospital, followed by fellowship in the Harvard Neonatal-Perinatal Fellowship Training Program. He did his post-doctoral research in the George Daley Laboratory at Boston Children’s Hospital.

    He is currently a neonatologist at Brigham & Women’s Hospital, where he serves as Medical Director of NICU. He is an Assistant Professor of Pediatrics at Harvard Medical School.

  • Testimonial

    Junjie Lu, PhD

    Post Doc / Senior Scientist

    About Junjie Lu, PhD

    Junjie obtained his PhD in 2011 at the Florida State University. His thesis work done in David Gilbert lab was focused on epigenetic regulation of genome replication. He has completed a project on copy number variation distribution during reprogramming and is now studying on the role of higher-order chromatin structure in regulation of alternative splicing using ATM deficient iPS cells as an experimental platform.

  • Testimonial

    Bryan Gorman

    PhD Candidate; Medical Engineering and Medical Physics; MIT - HST

    About Bryan Gorman

    Bryan did his undergraduate studies at Vanderbilt University in biomedical engineering and mathematics (B.E., M.S.). He has developed a Multi-scale imaging and informatics pipeline for in situ pluripotent stem cell analysis. This tool is essential for advanced tissue analysis because it enables one to accurately measure cellular relationships over multiple length scales and resolutions of tissue morphology. He plans to use this tool to perform analysis of heterogeneity at the transcriptional level using single molecule fluorescent in situ hybridization (smFISH), and combining such data with information from live-cell imaging prior to fixation — thus establishing a framework for generation of high-quality data for modeling cellular decision-making in heterogeneous tissues.

  • Testimonial

    Jeanne Carroll, MD

    Post Doc

    About Jeanne Carroll, MD

    Jeanne is a Harvard Neonatal-Perinatal Medicine Fellow. She earned her MD degree at the University of Virginia and completed pediatric residency at University of California, San Diego.

  • Testimonial

    Junning Wang

    Research Assistant II

    About Junning Wang

    Junning has been a research assistant at BWH since 2009 working for Professor Raju Kucherlapati and prior to that was a research fellow for 8 years. Her experience ranges from gene modification to mouse endoscopy!

  • Testimonial

    Sean McManus

    Research Assistant II

    About Sean McManus

    Sean earned his BS at Villanova University where he worked as a research assistant in a Biothermal Sciences Laboratory using high-speed video cryomicroscopy to study how cooling rates affect intracellular ice formation and cell viability. Since graduation he has been a research assistant in oncology clinical research at Millennium Pharmaceutical in Cambridge. He is enrolled in the Master of Science in Medical Sciences at Boston University School of Medicine and plans to go to medical school in 2016.

  • Testimonial

    Promise Okeke

    HSCI Summer Intern

    About Promise Okeke

    Originally from Nigeria, Promise earned the International President’s Scholarship from Augsburg College based on his outstanding high school performance and was able to come to the United States to pursue an undergraduate education. He plans to attend medical school and would like to continue research on stem cells. Prior to joining our lab he has worked in a stem cells lab at the University of Minnesota since January 2013 under Dr. Dan Kaufman.

  • Testimonial

    Faisal Naqib, PhD

    Summer Student - Harvard Newborn Medicine

    About Faisal Naqib, PhD

    Faisal is a medical student that University of Toronto. He has a PhD form McGill University, Department of Physiology – Spatial and temporal effects on molecular signaling networks.

Address

77 Avenue Louis Pasteur
Harvard Institutes of Medicine, Rm 823
Boston, MA, 02115

Contact

tel: (617) 525 5072
fax: (617) 525 5048
plerou@partners.org